COVID-19 Convalescent Plasma
COVID-19 Convalescent Plasma is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- The FDA issued an updated Emergency Use Authorization (EUA, 12/28/21) permitting the use of high-titer COVID-19 convalescent plasma only for patients who are immunosuppressed or receiving immunosuppressive therapy, whether hospitalized or ambulatory.
- The FDA EUA specifies the following:
- Only high titer plasma units are authorized for administration. COVID-19 convalescent plasma must be tested for anti-SARS-CoV-2 antibodies with 1 of 6 available kits (See Appendix A in 12/28/21 EUA)
- The administration should be initiated with 1 unit (200 mL).
- Additional convalescent plasma units may be administered based on the patient’s clinical response.
- Physicians should consider using COVID-19 convalescent plasmas among patients with impaired humoral immunity.
- Healthcare providers must make the FDA Fact Sheet for Patients and Parents/Caregivers available before use.
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INDICATIONS
FDA
FDA
- The FDA issued an updated Emergency Use Authorization (EUA, 12/28/21) permitting the use of high-titer COVID-19 convalescent plasma only for patients who are immunosuppressed or receiving immunosuppressive therapy, whether hospitalized or ambulatory.
- The FDA EUA specifies the following:
- Only high titer plasma units are authorized for administration. COVID-19 convalescent plasma must be tested for anti-SARS-CoV-2 antibodies with 1 of 6 available kits (See Appendix A in 12/28/21 EUA)
- The administration should be initiated with 1 unit (200 mL).
- Additional convalescent plasma units may be administered based on the patient’s clinical response.
- Physicians should consider using COVID-19 convalescent plasmas among patients with impaired humoral immunity.
- Healthcare providers must make the FDA Fact Sheet for Patients and Parents/Caregivers available before use.
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Last updated: January 14, 2022
Citation
Dzintars, Kathryn . "COVID-19 Convalescent Plasma." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Johns Hopkins Guides, www.hopkinsguide.com/hopkins/view/Johns_Hopkins_ABX_Guide/540631/all/COVID_19_Convalescent_Plasma.
Dzintars K. COVID-19 Convalescent Plasma. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://www.hopkinsguide.com/hopkins/view/Johns_Hopkins_ABX_Guide/540631/all/COVID_19_Convalescent_Plasma. Accessed March 20, 2023.
Dzintars, K. (2022). COVID-19 Convalescent Plasma. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguide.com/hopkins/view/Johns_Hopkins_ABX_Guide/540631/all/COVID_19_Convalescent_Plasma
Dzintars K. COVID-19 Convalescent Plasma [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2023 March 20]. Available from: https://www.hopkinsguide.com/hopkins/view/Johns_Hopkins_ABX_Guide/540631/all/COVID_19_Convalescent_Plasma.
* Article titles in AMA citation format should be in sentence-case
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